Early Rule-Out and Rule-In Strategies for Myocardial Infarction
نویسندگان
چکیده
منابع مشابه
Early Rule-Out and Rule-In Strategies for Myocardial Infarction.
BACKGROUND Patients with chest pain comprise a large proportion of emergency presentations and place a major burden on healthcare resources. Therefore, efforts to safely and rapidly identify those with and without acute myocardial infarction (AMI) are needed. The challenge for clinicians is to accurately identify patients with acute coronary syndromes, while balancing the need to safely and rap...
متن کاملOptimizing Early Rule-Out Strategies for Acute Myocardial Infarction: Utility of 1-Hour Copeptin.
BACKGROUND Combined testing of high-sensitivity cardiac troponin T (hs-cTnT) and copeptin at presentation provides a very high-although still imperfect-negative predictive value (NPV) for the early rule-out of acute myocardial infarction (AMI). We hypothesized that a second copeptin measurement at 1 h might further increase the NPV. METHODS In a prospective diagnostic multicenter study, we me...
متن کاملRapid Protocols to Rule out Myocardial Infarction.
Evidence Summary Cardiac troponin T and I are released into the bloodstream when cardiac muscle is damaged. Cardiac troponin tests have been available for decades and are the preferred biomarkers for the diagnosis of acute myocardial infarction (AMI).1 However, until recently, they lacked sensitivity in the first few hours following an acute myocardial injury. Therefore, AMI could not be ruled ...
متن کاملComparison of the Efficacy and Safety of Early Rule-Out Pathways for Acute Myocardial Infarction
BACKGROUND High-sensitivity cardiac troponin assays enable myocardial infarction to be ruled out earlier, but the optimal approach is uncertain. We compared the European Society of Cardiology rule-out pathway with a pathway that incorporates lower cardiac troponin concentrations to risk stratify patients. METHODS Patients with suspected acute coronary syndrome (n=1218) underwent high-sensitiv...
متن کاملCardiac troponin testing is overused after the rule-in or rule-out of myocardial infarction.
(type A MU) is one of the major components in overall MU. It is possible to achieve a small MU by improving the imprecision of the sample preparation procedure. Other than ensuring complete proteolysis, we observed that adding the isotope-labeled internal standard before pro-teolysis provided better imprecision than after proteolysis. This may allow a better control of the isotope ratio through...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2017
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2016.254730